Angel investments reported this month highlight the continued diversity of early-stage innovation across the ACA community. From healthcare breakthroughs and AI-powered enterprise tools to renewable energy advances and industrial process improvements, these deals demonstrate how angel groups are supporting founders tackling meaningful challenges across sectors and regions.
Below are the investments reported this month:
1—NIRA is a Danvers, Massachusetts-based company that Dermal Photonics’ NIRA Skin offers FDA-cleared, at-home non-ablative laser devices (NIRA Precision and Pro) designed to reduce fine lines and wrinkles by stimulating natural collagen production. It received a $10,000 investment from Boston, Massachusetts-based Sidecar Angels in Q1, 2025.
2—Synthio Chemicals, Inc. is a Boulder, Colorado-based company that a company that provides materials and design services to customers worldwide. The company specializes in the application of process intensification techniques to industrial-scale synthesis of fine and specialty chemicals. It received a $75,000 investment from Denver-based Rockies Ventures Club in Q4, 2025.
3—Tandem PV is a San Jose, California-based company that is manufacturing next-gen solar panels resulting in a 30-40% efficiency improvement over traditional silicon. It received a $160,000 investment from Phoenix, Arizona-based Arizona Tech Investors in Q3,2025.
4—Guardify is a Omaha, Nebraska-based company that provides a digital platform that makes evidence management safe, simple and secure. It received a $590,000 investment from Lincoln, Nebraska-based Nebraska Angels in Q4, 2025.
5—Oaken is an Indianapolis, Indiana-based company that provides simplifies lease management for agribusiness companies. It received a $360,000 investment from Lincoln, Nebraska-based Nebraska Angels in Q4, 2025.
6—Everykey is a Boulder, Colorado-based company that turns your phone into a smart key that replaces your passwords and keys. It received a $400,000 investment from Naples, Florida-based Tamiami Angel Fund in Q3, 2025.
7—LifeAir Medical is a Portland, Oregon-based company that is developing a device to minimize the spread of airborne pathogens in healthcare settings. It received a 4 $115,000 investment from St. louis, Missouri-based St. Louis Angels in q4, 2025.
8—Healonics is a Seattle, Washington-based company that is working to provide safer, more reliable means of bloodstream access for dialysis in patents with kidney failure. It received a $80,000 investment from Austin, Texas-based Central Texas Angel network in Q4,2025.
9—Endomedix is a Montclair, Hew Jersey-based company that works leverages work with long-term relationships with renowned scientific leaders to produce its specific expertise and polysaccharide science. It received a $85,000 investment from Austin, Texas-based central Texas Angel network in Q4, 2025.
10—Luminary Therapeutics is a Minneapolis, Minnesota-based company that is advancing allogeneic CAR-T therapy with a triple receptor CAR for autoimmune diseases and a split co-stimulatory CAR for solid tumors. It received a $350,000 investment from Minneapolis, Minnesota-based Gopher Angels in Q1, 2025.
11—SigmaSight is a Hermosa Beach, California-based company that is a AI-powered negotiation platform for insurers facing litigated claims. It received a $175,000 investment from Southern California-based TCA Venture Group in Q1, 2025.
12—Enhance Diagnostics is a Fayetteville, Arkansas-based company that is developing breath-based diagnostic devices for at-home and point-of-care monitoring of metabolic and kidney conditions. It received a $20,000 investment from Tucson, Arizona-based desert Angels in Q3, 2025.
Looking Ahead
These investments reflect the strength and diversity of angel-backed innovation across the country. From healthcare and diagnostics to renewable energy, enterprise software, consumer technology, and advanced manufacturing, angel groups continue to play a critical role in helping promising companies move from early traction toward scalable impact.
As more groups share their investment activity, the collective picture becomes clearer—demonstrating not only where capital is flowing, but how angels are supporting innovation in communities nationwide.
How to Participate
We encourage all ACA member groups to take part by sharing their investment and exit data with Deals to Destinations author and Data Analytics Chair Emeritus Rick Timmins, CTAN. If your group is interested in joining the rollout, please reach out to the ACA Data Analytics Committee team for details on how to contribute.
